Latest Episodes

Building The Seq Language For Bioinformatics - Episode 257

Bioinformatics is a complex and computationally demanding domain. The intuitive syntax of Python and extensive set of libraries make it a great language for bioinformatics projects, but it is hampered by the need for computational efficiency. Ariya Shajii created the Seq language to bridge the divide between the performance of languages like C and C++ and the ecosystem of Python with built-in support for commonly used genomics algorithms. In this episode he describes his motivation for creating a new language, how it is implemented, and how it is being...

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An Open Source Toolchain For Natural Language Processing From Explosion AI - Episode 256

The state of the art in natural language processing is a constantly moving target. With the rise of deep learning, previously cutting edge techniques have given way to robust language models. Through it all the team at Explosion AI have built a strong presence with the trifecta of SpaCy, Thinc, and Prodigy to support fast and flexible data labeling to feed deep learning models and performant and scalable text processing. In this episode founder and open source author Matthew Honnibal shares his experience growing a business around cutting edge...

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A Flexible Open Source ERP Framework To Run Your Business - Episode 255

Running a successful business requires some method of organizing the information about all of the processes and activity that take place. Tryton is an open source, modular ERP framework that is built for the flexibility needed to fit your organization, rather than requiring you to model your workflows to match the software. In this episode core developers Nicolas Évrard and Cédric Krier are joined by avid user Jonathan Levy to discuss the history of the project, how it is being used, and the myriad ways that you can adapt...

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Getting A Handle On Portable C Extensions With hpy - Episode 254

One of the driving factors of Python's success is the ability for developers to integrate with performant languages such as C and C++. The challenge is that the interface for those extensions is specific to the main implementation of the language. This contributes to difficulties in building alternative runtimes that can support important packages such as NumPy. To address this situation a team of developers are working to create the hpy project, a new interface for extension developers that is standardized and provides a uniform target for multiple runtimes....

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Open Source Machine Learning On Quantum Computers With Xanadu AI - Episode 253

Quantum computers promise the ability to execute calculations at speeds several orders of magnitude faster than what we are used to. Machine learning and artificial intelligence algorithms require fast computation to churn through complex data sets. At Xanadu AI they are building libraries to bring these two worlds together. In this episode Josh Izaac shares his work on the Strawberry Fields and Penny Lane projects that provide both high and low level interfaces to quantum hardware for machine learning and deep neural networks. If you are itching to get...

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The Advanced Python Task Scheduler - Episode 252

Most long-running programs have a need for executing periodic tasks. APScheduler is a mature and open source library that provides all of the features that you need in a task scheduler. In this episode the author, Alex Grönholm, explains how it works, why he created it, and how you can use it in your own applications. He also digs into his plans for the next major release and the forces that are shaping the improved feature set. Spare yourself the pain of triggering events at just the right time...

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Reducing The Friction Of Embedded Software Development With PlatformIO - Episode 251

Embedded software development is a challenging endeavor due to a fragmented ecosystem of tools. Ivan Kravets experienced the pain of programming for different hardware platforms when embroiled in a home automation project. As a result he built the PlatformIO ecosystem to reduce the friction encountered by engineers working with multiple microcontroller architectures. In this episode he describes the complexities associated with targeting multiple platforms, the tools that PlatformIO offers to simplify the workflow, and how it fits into the development process. If you are feeling the pain of working...

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APIs, Sustainable Open Source and The Async Web With Tom Christie - Episode 250

Tom Christie is probably best known as the creator of Django REST Framework, but his contributions to the state the web in Python extend well beyond that. In this episode he shares his story of getting involved in web development, his work on various projects to power the asynchronous web in Python, and his efforts to make his open source contributions sustainable. This was an excellent conversation about the state of asynchronous frameworks for Python and the challenges of making a career out of open source.

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Learning To Program Python By Building Video Games With Arcade - Episode 249

Video games have been a vehicle for learning to program since the early days of computing. Continuing in that tradition, Paul Craven created the Arcade library as a modern alternative to PyGame for use in his classroom. In this episode he explains his motivations for starting a new framework for video game development, his view on the benefits of games in computer education, and how his students and the broader community are using it to build interesting and creative projects. If you are looking for a way to get...

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Build Your Own Personal Data Repository With Nostalgia - Episode 248

The companies that we entrust our personal data to are using that information to gain extensive insights into our lives and habits while not always making those findings accessible to us. Pascal van Kooten decided that he wanted to have the same capabilities to mine his personal data, so he created the Nostalgia project to integrate his various data sources and query across them. In this episode he shares his motivation for creating the project, how he is using it in his day-to-day, and how he is planning to...

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